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1

In Vitro Selection of DNA Aptamers Against the HIV-1 TAR RNA Hairpin

Sekkai, Dalila, Dausse, Eric, Di Primo, Carmelo, Darfeuille, Fabien, Boiziau, Claudine, Toulmé, Jean-Jacques

Journal:

Antisense and Nucleic Acid Drug Development

Year:

2002

Language:

english

File:

PDF, 816 KB

english, 2002

2

QUENCHING OF TYROSINE FLUORESCENCE BY PHOSPHATE IONS: A MODEL STUDY FOR PROTEIN-NUCLEIC ACID COMPLEXES

Tula Alev-Behmoaras, Jean-Jacques Toulme, Claude Hélène

Journal:

Photochemistry and Photobiology

Year:

1979

Language:

english

File:

PDF, 455 KB

english, 1979

3

Aptamers: a new class of oligonucleotides in the drug discovery pipeline?

Eric Dausse, Sonia Da Rocha Gomes, Jean-Jacques Toulmé

Journal:

Current Opinion in Pharmacology

Year:

2009

Language:

english

File:

PDF, 192 KB

english, 2009

4

A Boost for the Emerging Field of RNA Nanotechnology

Shukla, Girish C., Haque, Farzin, Tor, Yitzhak, Wilhelmsson, L. Marcus, Toulmé, Jean-Jacques, Isambert, Hervé, Guo, Peixuan, Rossi, John J., Tenenbaum, Scott A., Shapiro, Bruce A.

Journal:

Year:

2011

Language:

english

File:

PDF, 3.75 MB

english, 2011

5

Identification of Aptamers Against the DNA Template for In Vitro Transcription of the HIV-1 TAR Element

BOIZIAU, CLAUDINE, DAUSSE, ERIC, MISHRA, RAKESH, DUCONGÉ, FRÉDÉRIC, TOULMÉ, JEAN-JACQUES

Journal:

Antisense and Nucleic Acid Drug Development

Year:

1997

Language:

english

File:

PDF, 18.17 MB

english, 1997

6

A combinatorial approach to the repertoire of RNA kissing motifs; towards multiplex detection by switching hairpin aptamers

Durand, Guillaume, Dausse, Eric, Goux, Emma, Fiore, Emmanuelle, Peyrin, Eric, Ravelet, Corinne, Toulmé, Jean-Jacques

Journal:

Nucleic Acids Research

Year:

2016

Language:

english

File:

PDF, 2.50 MB

english, 2016

7

Electrostatics explains the position-dependent effect of G*U wobble base pairs on the affinity of RNA kissing complexes

Abi-Ghanem, Josephine, Rabin, Clémence, Porrini, Massimiliano, Dausse, Eric, Toulmé, Jean-Jacques, Gabelica, Valérie

Journal:

Year:

2017

Language:

english

File:

PDF, 2.24 MB

english, 2017

8

Aptamers in Bordeaux 2017: An exceptional “millésime”

Toulmé, Jean-Jacques, Azéma, Laurent, Darfeuille, Fabien, Dausse, Eric, Durand, Guillaume, Paurelle, Olivier

Journal:

Year:

2018

Language:

english

File:

PDF, 674 KB

english, 2018

9

Use of the Fluorescent Nucleoside Analogue Benzo[g]quinazoline 2′-O-Methyl-β-D-ribofuranoside to Monitor the Binding of the HIV-1 Tat Protein or of Antisense Oligonucleotides to the TAR RNA Stem-Loop

Andrey Arzumanov, Frédéric Godde, Serge Moreau, Jean-Jacques Toulmé, Alan Weeds, Michael J. Gait

Journal:

Helvetica Chimica Acta

Year:

2000

Language:

english

File:

PDF, 315 KB

english, 2000

10

Use of Dynamic Combinatorial Chemistry for the Identification of Covalently Appended Residues that Stabilize Oligonucleotide Complexes

Anthony Bugaut, Jean-Jacques Toulmé, Bernard Rayner

Journal:

Angewandte Chemie

Year:

2004

Language:

english

File:

PDF, 121 KB

english, 2004

11

Deciphering Aromatic Oligoamide Foldamer–DNA Interactions

Dr. Laurence Delaurière, Dr. Zeyuan Dong, Dr. Katta Laxmi-Reddy, Dr. Frédéric Godde, Dr. Jean-Jacques Toulmé, Dr. Ivan Huc

Journal:

Angewandte Chemie

Year:

2012

Language:

english

File:

PDF, 973 KB

english, 2012

12

Use of Dynamic Combinatorial Chemistry for the Identification of Covalently Appended Residues that Stabilize Oligonucleotide Complexes

Anthony Bugaut, Jean-Jacques Toulmé, Bernard Rayner

Journal:

Angewandte Chemie International Edition

Year:

2004

Language:

english

File:

PDF, 122 KB

english, 2004

13

Deciphering Aromatic Oligoamide Foldamer–DNA Interactions

Dr. Laurence Delaurière, Dr. Zeyuan Dong, Dr. Katta Laxmi-Reddy, Dr. Frédéric Godde, Dr. Jean-Jacques Toulmé, Dr. Ivan Huc

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 997 KB

english, 2012

14

Probing the Interactions of the Anticancer Drug Doxorubicin with Polymeric Nanoparticles Using Fluorescence Spectroscopy

Nelly Henry-Toulmé, Anne Decout, Jacqueline Lalanne, Fariba Nemati, Catherine Dubernet, Jean Dufourcq

Journal:

Journal of Colloid and Interface Science

Year:

1994

File:

PDF, 428 KB

1994

15

Stacking interactions between aromatic amino acids and adenine ring of ATP in zinc mediated ternary complexes

Jean-Jacques Toulme

Journal:

Bioinorganic Chemistry

Year:

1978

Language:

english

File:

PDF, 703 KB

english, 1978

16

Towards the selection of phosphorothioate aptamers : Optimizing in vitro selection steps with phosphorothioate nucleotides

Marie-Line Andreola, Christina Calmels, Justine Michel, Jean-Jacques Toulmé, Simon Litvak

Journal:

Year:

2000

Language:

english

File:

PDF, 728 KB

english, 2000

17

HAPIscreen, a method for high-throughput aptamer identification

Eric Dausse, Saïd Taouji, Laetitia Evadé, Carmelo Di Primo, Eric Chevet, Jean-Jacques Toulmé

Journal:

Journal of Nanobiotechnology

Year:

2011

Language:

english

File:

PDF, 1.01 MB

english, 2011

18

A tryptophan-containing peptide recognizes and cleaves DNA at apurinic sites

Behmoaras, Tula, Toulmé, Jean-Jacques, Hélène, Claude

Journal:

Year:

1981

File:

PDF, 474 KB

1981

19

10.1038/83451

Toulmé, Jean-Jacques

Journal:

Nature Biotechnology

Year:

2001

Language:

english

File:

PDF, 68 KB

english, 2001

20

Anti-HIV Activity of Steric Block Oligonucleotides

GABRIELA IVANOVA, ANDREY A. ARZUMANOV, JOHN J. TURNER, SANDRINE REIGADAS, JEAN-JACQUES TOULMÉ, DOUGLAS E. BROWN, ANDREW M.L. LEVER, MICHAEL J. GAIT

Journal:

Annals of the New York Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 121 KB

english, 2006

21

Benzoquinazoline Derivatives as Substitutes for Thymine in Nucleic Acid Complexes. Use of Fluorescence Emission of Benzo[g]quinazoline-2,4-(1H,3H)-dione in Probing Duplex and Triplex Formation†

Godde, Frédéric, Toulmé, Jean-Jacques, Moreau, Serge

Journal:

Year:

1998

Language:

english

File:

PDF, 217 KB

english, 1998

22

Relative contribution of photo-addition, helper oligonucleotide and RNase H to the antisense effect of psoralen-oligonucleotide conjugates, on in vitro translation of Leishmania mRNAs

Emanuelle Pascolo, Denis Hudrisier, Brian Sproat, Nguyen T. Thuong, Jean-Jacques Toulme

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1994

Language:

english

File:

PDF, 901 KB

english, 1994

23

Improved leishmanicidal effect of phosphorotioate antisense oligonucleotides by LDL-mediated delivery

Rakesh Kumar Mishra, Catherine Moreau, Claude Ramazeilles, Serge Moreau, Jacques Bonnet, Jean-Jacques Toulmé

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1995

Language:

english

File:

PDF, 842 KB

english, 1995

24

Modulating viral gene expression by aptamers to RNA structures

Jean-Jacques Toulmé, Fabien Darfeuille, Gaëlle Kolb, Sandrine Chabas, Cathy Staedel

Journal:

Biology of the Cell

Year:

2003

Language:

english

File:

PDF, 154 KB

english, 2003

25

A maximum of two tryptophan residues in gene-32 protein from phage T4 undergo stacking interactions with single-stranded polynucleotides

José R. CASAS-FINET, Jean-Jacques TOULMÉ, René SANTUS, August H. MAKI

Journal:

Year:

1988

Language:

english

File:

PDF, 630 KB

english, 1988

26

Interactions of aromatic residues of proteins with nucleic acids. Fluorescence studies of the binding of oligopeptides containing tryptophan and tyrosine residues to polynucleotides

Brun, Francine, Toulme, Jean J., Helene, Claude

Journal:

Year:

1975

Language:

english

File:

PDF, 698 KB

english, 1975

27

Fluorescence study of the association between gene 32 protein of bacteriophage T4 and poly(1-N6-ethenoadenylic acid). Evidence for energy transfer

Jean Jacques Toulmé, Claude Hélène

Journal:

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis

Year:

1980

Language:

english

File:

PDF, 621 KB

english, 1980

28

Interaction of a tryptophan-containing peptide with chromatin core particles: A fluorescence study

Vincent Colot, Jean-Jacques Toulme, Claude Helene

Journal:

Year:

1984

Language:

english

File:

PDF, 555 KB

english, 1984

29

Blockage of AM V reverse transcriptase by antisense oligodeoxynucleotides

Nadine Loreau, Claudine Boiziau, Philippe Verspieren, David Shire, Jean-Jacques Toulmé

Journal:

Year:

1990

Language:

english

File:

PDF, 411 KB

english, 1990

30

A phosphorothioate oligonucleotide blocks reverse transcription via an antisense mechanism

Claudine Boiziau, Serge Moreau, Jean-Jacques Toulmé

Journal:

Year:

1994

Language:

english

File:

PDF, 653 KB

english, 1994

31

Chimeric alpha-beta oligonucleotides as antisense inhibitors of reverse transcription

Claudine Boiziau, Françoise Debart, Bernard Rayner, Jean-Louis Imbach, Jean-Jacques Toulme

Journal:

Year:

1995

Language:

english

File:

PDF, 566 KB

english, 1995

32

Determinants of apical loop–internal loop RNA–RNA interactions involving the HCV IRES

Sonia Da Rocha Gomes, Eric Dausse, Jean-Jacques Toulmé

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 1.68 MB

english, 2004

33

LNA derivatives of a kissing aptamer targeted to the trans-activating responsive RNA element of HIV-1

Isabelle Lebars, Tristan Richard, Carmelo Di Primo, Jean-Jacques Toulmé

Journal:

Blood Cells, Molecules, and Diseases

Year:

2007

Language:

english

File:

PDF, 372 KB

english, 2007

34

Nucleic acids targeted to drugs: SELEX against a quadruplex ligand

Amandine Renaud de la Faverie, Florian Hamon, Carmelo Di Primo, Eric Largy, Eric Dausse, Laurence Delaurière, Corinne Landras-Guetta, Jean-Jacques Toulmé, Marie-Paule Teulade-Fichou, Jean-Louis Mergny

Journal:

Year:

2011

Language:

english

File:

PDF, 1.18 MB

english, 2011

35

Regulating eukaryotic gene expression with aptamers

Jean-Jacques Toulmé, Carmelo Di Primo, David Boucard

Journal:

Year:

2004

Language:

english

File:

PDF, 210 KB

english, 2004

36

Les aptamères : du concept à l’outil

Jean-Jacques Toulmé, Sonia Da Rocha, Eric Dausse, Laurent Azéma, Isabelle Lebars, Serge Moreau

Journal:

Médecine Nucléaire

Year:

2007

File:

PDF, 347 KB

2007

37

Binding of oligopyrimidines to the RNA hairpin responsible for the ribosome gag-pol frameshift in HIV-1

Karine Aupeix, Réjane Le Tinévez, Jean-Jacques Toulmé

Journal:

Year:

1999

Language:

english

File:

PDF, 213 KB

english, 1999

38

Specific regulation of gene expression by antisense, sense and antigene nucleic acids

Claude Hélène, Jean-Jacques Toulmé

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1990

Language:

english

File:

PDF, 2.88 MB

english, 1990

39

Advances in binder identification and characterisation: the case of oligonucleotide aptamers

Saïd Taouji, Eric Dausse, Laetitia Evadé, Carmelo Di Primo, Jean-Jacques Toulmé, Eric Chevet

Journal:

New Biotechnology

Year:

2012

Language:

english

File:

PDF, 390 KB

english, 2012

40

Tricyclo-DNA Containing Oligonucleotides as Steric Block Inhibitors of Human Immunodeficiency Virus Type 1 Tat-Dependent Trans -Activation and HIV-1 Infectivity

Ivanova, Gabriela, Reigadas, Sandrine, Ittig, Damian, Arzumanov, Andrey, Andreola, Marie-Line, Leumann, Christian, Toulmé, Jean-Jacques, Gait, Michael J.

Journal:

Oligonucleotides

Year:

2007

Language:

english

File:

PDF, 293 KB

english, 2007

41

Encapsidation of RNA–Polyelectrolyte Complexes with Amphiphilic Block Copolymers: Toward a New Self-Assembly Route

Bui, Laurent, Abbou, Scarlette, Ibarboure, Emmanuel, Guidolin, Nicolas, Staedel, Cathy, Toulmé, Jean-Jacques, Lecommandoux, Sébastien, Schatz, Christophe

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 3.57 MB

english, 2012

42

Systematic screening of LNA/2′-O-methyl chimeric derivatives of a TAR RNA aptamer

Carmelo Di Primo, Ivo Rudloff, Sandrine Reigadas, Andrey A. Arzumanov, Michael J. Gait, Jean-Jacques Toulmé

Journal:

Year:

2007

Language:

english

File:

PDF, 109 KB

english, 2007

43

Absorption and fluorescence studies of the binding of the recA gene product from E. coli to single-stranded and double-stranded DNA. Ionic strength dependence

Christian Cazenave, Marie Chabbert, Jean-Jacques Toulme, Claude Helene

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1984

Language:

english

File:

PDF, 502 KB

english, 1984

44

Specific recognition by the tripeptide lysyl-tryptophyl-α-lysine of structural damage induced in DNA by platinum derivatives

Trung Le Doan, Michèle Guigues, Jean-Jacques Toulmé, Claude Hélène

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1985

Language:

english

File:

PDF, 506 KB

english, 1985

45

SELEX and dynamic combinatorial chemistry interplay for the selection of conjugated RNA aptamers

Bugaut, Anthony, Toulm?, Jean-Jacques, Rayner, Bernard

Journal:

Organic & Biomolecular Chemistry

Year:

2006

Language:

english

File:

PDF, 219 KB

english, 2006

46

Hexitol Nucleic Acid-Containing Aptamers Are Efficient Ligands of HIV-1 TAR RNA †

Kolb, Gaëlle, Reigadas, Sandrine, Boiziau, Claudine, van Aerschot, Arthur, Arzumanov, Andrey, Gait, Michael J., Herdewijn, Piet, Toulmé, Jean-Jacques

Journal:

Year:

2005

Language:

english

File:

PDF, 287 KB

english, 2005

47

99m Tc-MAG3-Aptamer for Imaging Human Tumors Associated with High Level of Matrix Metalloprotease-9

Da Rocha Gomes, Sonia, Miguel, Julie, Azéma, Laurent, Eimer, Sandrine, Ries, Colette, Dausse, Eric, Loiseau, Hugues, Allard, Michèle, Toulmé, Jean-Jacques

Journal:

Bioconjugate Chemistry

Year:

2012

Language:

english

File:

PDF, 2.82 MB

english, 2012

48

DNA Aptamers Selected against the HIV-1 RNase H Display in Vitro Antiviral Activity †

Andreola, Marie-Line, Pileur, Frédéric, Calmels, Christina, Ventura, Michel, Tarrago-Litvak, Laura, Toulmé, Jean-Jacques, Litvak, Simon

Journal:

Year:

2001

Language:

english

File:

PDF, 124 KB

english, 2001

49

Single-strand binding proteins from phage T4 and E. coli form higher order structures with poly(dT)

Boidot-Forget, Marc, Saison-Behmoaras, Tula, Toulmé, Jean-Jacques, Hélène, Claude

Journal:

Year:

1986

Language:

english

File:

PDF, 1.68 MB

english, 1986

50

Effect of phosphate ions on the fluorescence of tryptophan derivatives

Alev-Behmoaras, Tula, Toulmé, Jean-Jacques, Hélène, Claude

Journal:

Year:

1979

Language:

english

File:

PDF, 321 KB

english, 1979